| Insider | Role | Shares | Value | Buys | Sells |
|---|---|---|---|---|---|
| Date | Ticker | Insider | Role | Type | Shares | Price | Value | Chg% | SEC |
|---|---|---|---|---|---|---|---|---|---|
| Insider | Role | Shares | Value | Buys | Sells |
|---|---|---|---|---|---|
| Date | Ticker | Insider | Role | Type | Shares | Price | Value | Chg% | SEC |
|---|---|---|---|---|---|---|---|---|---|
Director
1 company
Joseph Klein III is Director at IONS. Joseph Klein III's net worth is not public. Form 4 filings only show shares in the companies where this person is an insider; those holdings are worth an estimated $445K at current prices.
Our model assigns Joseph Klein III a middling insider score of 62/100, based on 14 past trades. Over a 12-month horizon, 55.6% of those trades were profitable, with an average 12-month return of +1.7%.
The IONS filings lean toward selling, a net 176,205 shares.
Joseph Klein III has 29 Form 4 filings on record from July 2019 to July 2026, all as Director at Ionis Pharmaceuticals (IONS), 2019–2026.
The 85 reported transactions were 35 open-market sales, 34 option exercises and 16 option or other derivative awards.
Counted by filing, the open-market trades come to no purchases and 22 sales worth about $11.4M.
The largest open-market sale was 21,332 shares of IONS at an average $79.51 on March 3, 2026, about $1.7M.
11 of the 12 sales since April 2023 were made under a Rule 10b5-1 trading plan; the other was not.
| Date | Ticker | Role | Type | Shares | Price | Value | Chg% | 3M | 12M | SEC |
|---|---|---|---|---|---|---|---|---|---|---|
| Jul 1, 2026 | IONS Ionis Pharmaceuticals, Inc. | Director | Sale+OE10b5-1 | 11,518 | $79.04 | $910,416.46 | -51.1% | -42.1% | - | |
| May 1, 2026 | IONS Ionis Pharmaceuticals, Inc. | Director | Sale+OE10b5-1 | 10,111 | $73.51 | $743,238.27 | -47.9% | -29.2% | - | |
| Apr 1, 2026 | IONS Ionis Pharmaceuticals, Inc. | Director | Sale+OE10b5-1 | 22,321 | $75.55 | $1,686,301.88 | -67.0% | +5.5% | - | |
| Mar 3, 2026 | IONS Ionis Pharmaceuticals, Inc. | Director | Sale+OE10b5-1 | 21,332 | $79.51 | $1,696,181.37 | -65.9% | -4.2% | - | |
| Nov 25, 2025 | IONS Ionis Pharmaceuticals Inc | Director | Sale+OE10b5-1 | 12,000 | $80.00 | $960,000.00 | - | +4.5% | - | |
| Sep 3, 2025 | IONS Ionis Pharmaceuticals Inc | Director | Sale+OE10b5-1 | 28,000 | $60.00 | $1,680,000.00 | - | +34.4% | -3.9% | |
| Sep 3, 2025 | IONS Ionis Pharmaceuticals Inc | Director | Sale+OE10b5-1 | 28,000 | $60.00 | $1,680,000.00 | - | +34.4% | -3.9% | |
| Jul 16, 2024 | IONS Ionis Pharmaceuticals Inc | Director | Sale+OE10b5-1 | 12,000 | $50.00 | $600,000.00 | - | -22.5% | -14.2% | |
| May 3, 2024 | IONS Ionis Pharmaceuticals Inc | Director | Sell10b5-1 | 6,000 | $42.71 | $256,276.57 | -100% | +22.3% | -21.9% | |
| Nov 15, 2023 | IONS Ionis Pharmaceuticals Inc | Director | Sell10b5-1 | 2,000 | $50.00 | $100,000.00 | -10.9% | -2.3% | -25.2% |